Living Myocardial Slices (LMS) are a novel preparation of intermediate complexity that can be used to study heart biology. LMS possess complex 3D structure, heterocellularity and intact extracellular matrix that makes them ideal for functional and structural studies. LMS can be prepared from several species, including human. Multiple slices can be produced from each biopsy, producing several samples for experimentation. LMS are highly viable, stable in culture and can be used for toxicology and pharmacology experiments, to study pathophysiology and treatments for cardiac disease.

While LMS are prepared by a straightforward method - simple mechanical dissociation using a vibrating microtome, several essential details contribute to the quality and viability, and this explains the variability of results in different laboratories. This workshop will discuss LMS in the context of other myocardial in-vitro models, highlighting strengths and limitations of the technique, demonstrating the preparation of this model and offering the participants a hands-on opportunity to learn this technique.

Enquiries

Sam Reitemeier (s.reitemeier@imperial.ac.uk)

Dates

20 - 21 November 2025

This online 'Introductory Medical Statistics Course’ introduces you to basic statistical concepts.  It runs from the afternoon of Thursday 13 November to the morning of Friday 14 November (one day in total), and is run by statisticians and epidemiologists based at the National Heart and Lung Institute (NHLI), part of Imperial College.  
Further details here: https://www.medstatscourse.co.uk/ 
* NB: when booking, Please state your name and title exactly as you wish them to appear on your attendance certificate - thank you.

Fees

please see details regarding our fees here: https://www.medstatscourse.co.uk/ - and select the rate applicable to you.

MSc/PhD Students: £120 - you must be a full time student without another source of income

Academic/NHS/Charities: £190 - those working in the NHS, at a university or in the charitable sector

Corporate/other: £240 - those working in the private sector

Please note that Imperial College staff and students can pay via internal journal/transfer, using an Imperial College finance code, with their supervisor’s/group’s permission, and if they have a valid code.  Please contact Magda Wheatley on m.wheatley@imperial.ac.uk for further details (you don’t then need to book online). 

Enquiries

Please contact m.wheatley@imperial.ac.uk